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KMID : 0104920170260010019
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Journal of Hawhwa Medicine
2017 Volume.26 No. 1 p.19 ~ p.24
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The anti-coagulation effect of natural carbonated hot spring water on DNCB-induced NC/Nga mice
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Jang Soon-Woo
Park Jung-Hwan
Kwak Jin-Young
Kho Young-Mee
Ahn Taek-Won
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Abstract
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Objectives:Spring water is widely known to relax muscles bypromoting blood circulation. This study was conducted to analyze theantithrombotic effect of naturally carbonated hot spring water (NCHW) to assessits influence on blood circulation.
Methods:Atopic dermatitis was induced in the skin of the miceused in this experiment. NCHW was applied, and the antithrombotic effect was assessedand compared with that of other interventions. The positive control group was treatedorally with aspirin.
Results:After 3 weeks of exposure to NCHW, the experimental groupshowed a significant antithrombotic effect. NCHW also produced inhibitoryresponses to both collagen- and ADP-induced platelet aggregation, whereas the groupgiven aspirin reacted only to collagen-induced platelet aggregation.
Conclusions:The experimentdemonstrated the intrinsic antithrombotic effects of NCHW compared with thoseof artificially carbonated water, tap water, and aspirin. This result suggests thepossibility that NCHW can be used as a supportive and alternative treatment forvascular diseases.
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KEYWORD
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NCHW(Natural carbonated hot spring water), coagulation
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